Decreased Toll-like receptor-2 messenger ribonucleic acid and increased Toll-like receptor-4 in the tubal epithelium next to the infiltrated trophoblasts during tubal pregnancy.

Dec 14, 2020 Antibodies

Decreased Toll-like receptor-2 messenger ribonucleic acid and increased Toll-like receptor-4 in the tubal epithelium next to the infiltrated trophoblasts during tubal pregnancy.

Thirty-seven women undergo a salpinctomy for the ampullary pregnancy of the tubal and nine non-flame retardant patients with benign or appended uterine disease.
Oviducol tissues with ectopic gestures were separated from the location site (Group 1) and the nonimplantation site (Group 2). The tissues of ampullary fallopiel tubes during the median phase (group 3) were collected as a control group. Immunohistochemistry and reaction of the quantitative real-time polymerase chain were performed.
Differences in TLR2 and TLR4 expression models between group 1 and group 2 and between the speaker group (combined group 1 and group 2) and the unobstructed group

The comparison of the pregnant group with group 3, the TLR4 messaging RNA (mRNA) and proteins have been considerably regulated in the pregnant group. On the other hand, the TLR2 mRNA was considerably regulated, while the TLR2 protein presented a downward trend. The detailed analysis between group 1 and group 3 revealed a significantly higher TLR2 and TLR4 protein in group 1. In terms of mRNA expression, it was always shown that the expression of the TLR4 was considerably Increased in Group 1, while the TLR2 expression was significantly reduced in group 1.
The decrease in TLR2 mRNA and an increase in TLR4 in tubal epithelial cells next to the infiltrated trophoblasts may be associated with aspects of the pathophysiology of tubular ectopic pregnancy in immune defense. Most viral infections are controlled by the innate and adaptive immune system. An amazingly limited number of schema recognition receivers (PRRs) have the ability to detect a wide variety of viral infections.

The reason for the extensive activity of PRR lies in the ability to recognize viral nucleic acids. These nucleic acids lack signatures present in cytoplasmic cellular nucleic acids and thus marking them in the form of pathogen. The accumulated evidence suggests that these signatures, which are mainly detected by an PRR class called retinoic inducible gene receptors I (RIG-I) – receivers and other proteins, are not unique to viruses, but rather resemble Immature forms of cellular ribonucleic acids generated by cellular polymerases.

Expression profiling of differential micro-ribonucleic acid in ovarian endometrioma with treatment of leuprolide acetate.

GOAL
Micro-ribonucleic acids (MIRNAS) play an important pathological role in endometriosis. Leuprolide acetate, a gonadotropin hormone analogue, is widely used to treat endometriosis; However, the molecular mechanisms involved in endometriotic tissue regression remain uncertain. We performed the expression of mirna profiling from ovarian clinical endometrioma for an overview of the effects of leuprolide acetate treatment.

Methods
We have obtained clinical samples from nine normal eteopal endometrium, eight ovarian endometriotic and 12 endometriotic tissues treated with leuprolide acetate. We compared Mirna’s expression profiles of the three groups by performing a Microna Taqman Array card and a bioinformatic analysis.

RESULTS
Two Mirnas, MIR-939 and MIR-154, have been regulated in endometriotic tissues and decreased in the endometriotic tissue treated with leuprolide acetate. Five MIRNAS (MIR-146A, MIR-142-3P, MIR-136 *, MIR-125B-1 * and MIR-15B *) were unchanged in endometriotic tissues, but were regulated under the treatment of leuprolide acetate .

 Decreased Toll-like receptor-2 messenger ribonucleic acid and increased Toll-like receptor-4 in the tubal epithelium next to the infiltrated trophoblasts during tubal pregnancy.
Decreased Toll-like receptor-2 messenger ribonucleic acid and increased Toll-like receptor-4 in the tubal epithelium next to the infiltrated trophoblasts during tubal pregnancy.

Lowering Messenger 2-4.9 ribonucleic acid toll receptors in peripheral blood mononuclear cells in the beneficiaries of the kidney allograft, the immunosuppressive processing and the actual graft function occur.

CONTEXT
Tacrolimus (TAC) and Cyclosporine (CSA) inhibit mononuclear cells of peripheral blood (PBMC) after stimulating various toll receptors (TLR) at supra-pharmacological concentrations. Previous studies have shown that 24 hours after the transplant of the kidneys (KT), the expression of the TLR4 courier RNA (mRNA) in PBMC of patients with subsequent delayed graft (DGF +) was lower than that of the Patients without DGF (DGF-). An evaluation was made up of the interaction of the immunosuppression with the TLR mRNA in the PBMC and to verify whether the reduced expression of the mRNA of TLR-2,3,4,9 in PBMC is permanent in the DGF +.

Methods
We studied the expression of TLR mRNA in unstally stimulated PBMC. All patients were transplanted more than a month before the acquisition of PBMC. Patients were divided into groups compared to the positive or negative history of the delayed graft function (DGF +/-).

RESULTS
The expression of TLR2, TLR3 and TLR9 in patients was lower than that of the control group. We found a TAC C0 association with TLR4 expression only and the dose of the CSA by 1 kg of body weight with TLR2 or up to 6 months after KT with TLR9. Muffetil mycophenolate (MMF) contributed to the change of expression TLR4 in the CSA group but not in the TAC group. TLR3 and TLR9 were almost also sensitive to the TAC and CSA, with a decrease in the expression in relation to the control. DGF + was associated with the degree of variable reduction of TLR2, TLR3, TLR4 and TLR 9.

RNA Polymerase II/Poll II

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EUR 1725

POLR2B, ID (POLR2B, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140kD polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2)

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EUR 695

POLR2B, ID (POLR2B, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140kD polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2)

MBS644175-5x02mL 5x0.2mL
EUR 2975

POLR2B, ID (POLR2B, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140kD polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2) (AP)

MBS6335686-02mL 0.2mL
EUR 980

POLR2B, ID (POLR2B, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140kD polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2) (AP)

MBS6335686-5x02mL 5x0.2mL
EUR 4250

POLR2B, ID (POLR2B, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140kD polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2) (APC)

MBS6335687-02mL 0.2mL
EUR 980

POLR2B, ID (POLR2B, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140kD polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2) (APC)

MBS6335687-5x02mL 5x0.2mL
EUR 4250

POLR2B, ID (POLR2B, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140kD polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2) (Biotin)

MBS6335688-02mL 0.2mL
EUR 980

POLR2B, ID (POLR2B, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140kD polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2) (Biotin)

MBS6335688-5x02mL 5x0.2mL
EUR 4250

POLR2B, ID (POLR2B, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140kD polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2) (FITC)

MBS6335689-02mL 0.2mL
EUR 980

POLR2B, ID (POLR2B, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140kD polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2) (FITC)

MBS6335689-5x02mL 5x0.2mL
EUR 4250

POLR2B, ID (POLR2B, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140kD polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2) (PE)

MBS6335696-02mL 0.2mL
EUR 980

POLR2B, ID (POLR2B, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140kD polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2) (PE)

MBS6335696-5x02mL 5x0.2mL
EUR 4250

POLR2G (DNA-directed RNA Polymerase II Subunit RPB7, RNA Polymerase II Subunit B7, DNA-directed RNA Polymerase II Subunit G, RNA Polymerase II 19kD Subunit, RPB19, RPB7)

MBS644436-01mg 0.1mg
EUR 655

POLR2G (DNA-directed RNA Polymerase II Subunit RPB7, RNA Polymerase II Subunit B7, DNA-directed RNA Polymerase II Subunit G, RNA Polymerase II 19kD Subunit, RPB19, RPB7)

MBS644436-5x01mg 5x0.1mg
EUR 2800

POLR2B, ID (POLR2B, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140kD polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2) (MaxLight 405)

MBS6335691-01mL 0.1mL
EUR 980

POLR2B, ID (POLR2B, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140kD polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2) (MaxLight 405)

MBS6335691-5x01mL 5x0.1mL
EUR 4250

POLR2B, ID (POLR2B, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140kD polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2) (MaxLight 490)

MBS6335692-01mL 0.1mL
EUR 980

POLR2B, ID (POLR2B, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140kD polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2) (MaxLight 490)

MBS6335692-5x01mL 5x0.1mL
EUR 4250

POLR2B, ID (POLR2B, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140kD polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2) (MaxLight 550)

MBS6335693-01mL 0.1mL
EUR 980

POLR2B, ID (POLR2B, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140kD polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2) (MaxLight 550)

MBS6335693-5x01mL 5x0.1mL
EUR 4250

POLR2B, ID (POLR2B, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140kD polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2) (MaxLight 650)

MBS6335694-01mL 0.1mL
EUR 980

POLR2B, ID (POLR2B, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140kD polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2) (MaxLight 650)

MBS6335694-5x01mL 5x0.1mL
EUR 4250

POLR2B, ID (POLR2B, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140kD polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2) (MaxLight 750)

MBS6335695-01mL 0.1mL
EUR 980

POLR2B, ID (POLR2B, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140kD polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2) (MaxLight 750)

MBS6335695-5x01mL 5x0.1mL
EUR 4250

POLR2B, ID (POLR2B, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140kD polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2) (Azide free) (HRP)

MBS6335690-02mL 0.2mL
EUR 980

POLR2B, ID (POLR2B, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II 140kD polypeptide, DNA-directed RNA polymerase II subunit B, RNA polymerase II subunit 2, RNA polymerase II subunit B2) (Azide free) (HRP)

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EUR 4250

RNA Polymerase II antibody

10R-R116a 100 uL
EUR 548
Description: Mouse monoclonal RNA Polymerase II antibody

RNA Polymerase II antibody

10R-2395 5 mL
EUR 318
Description: Mouse monoclonal RNA Polymerase II antibody

RNA Polymerase II, Antibody

GWB-3F12B0 0.1 ml Ask for price

RNA polymerase II Antibody

GWB-5B03A0 0.1 mg Ask for price

RNA Polymerase II antibody

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EUR 705

RNA Polymerase II antibody

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EUR 3025

POLR2C (DNA-directed RNA Polymerase II Subunit RPB3, RNA Polymerase II Subunit 3, RNA Polymerase II Subunit B3, DNA-directed RNA Polymerase II 33kD Polypeptide, RPB33, DNA-directed RNA Polymerase II Subunit C, RPB31, A-152E5.7) (AP)

MBS6133047-01mL 0.1(mL
EUR 875

POLR2C (DNA-directed RNA Polymerase II Subunit RPB3, RNA Polymerase II Subunit 3, RNA Polymerase II Subunit B3, DNA-directed RNA Polymerase II 33kD Polypeptide, RPB33, DNA-directed RNA Polymerase II Subunit C, RPB31, A-152E5.7) (AP)

MBS6133047-5x01mL 5x0.1mL
EUR 3800

POLR2C (DNA-directed RNA Polymerase II Subunit RPB3, RNA Polymerase II Subunit 3, RNA Polymerase II Subunit B3, DNA-directed RNA Polymerase II 33kD Polypeptide, RPB33, DNA-directed RNA Polymerase II Subunit C, RPB31, A-152E5.7) (PE)

MBS6159562-01mL 0.1(mL
EUR 875

POLR2C (DNA-directed RNA Polymerase II Subunit RPB3, RNA Polymerase II Subunit 3, RNA Polymerase II Subunit B3, DNA-directed RNA Polymerase II 33kD Polypeptide, RPB33, DNA-directed RNA Polymerase II Subunit C, RPB31, A-152E5.7) (PE)

MBS6159562-5x01mL 5x0.1mL
EUR 3800

POLR2D (DNA-directed RNA Polymerase II Subunit RPB4, DNA-directed RNA Polymerase II Subunit D, RNA Polymerase II 16kD Subunit)

MBS648304-01mg 0.1mg
EUR 630

POLR2D (DNA-directed RNA Polymerase II Subunit RPB4, DNA-directed RNA Polymerase II Subunit D, RNA Polymerase II 16kD Subunit)

MBS648304-5x01mg 5x0.1mg
EUR 2680

POLR2C (DNA-directed RNA Polymerase II Subunit RPB3, RNA Polymerase II Subunit 3, RNA Polymerase II Subunit B3, DNA-directed RNA Polymerase II 33kD Polypeptide, RPB33, DNA-directed RNA Polymerase II Subunit C, RPB31, A-152E5.7) APC

MBS6138350-01mL 0.1(mL
EUR 875

POLR2C (DNA-directed RNA Polymerase II Subunit RPB3, RNA Polymerase II Subunit 3, RNA Polymerase II Subunit B3, DNA-directed RNA Polymerase II 33kD Polypeptide, RPB33, DNA-directed RNA Polymerase II Subunit C, RPB31, A-152E5.7) APC

MBS6138350-5x01mL 5x0.1mL
EUR 3800

POLR2C (DNA-directed RNA Polymerase II Subunit RPB3, RNA Polymerase II Subunit 3, RNA Polymerase II Subunit B3, DNA-directed RNA Polymerase II 33kD Polypeptide, RPB33, DNA-directed RNA Polymerase II Subunit C, RPB31, A-152E5.7) (Biotin)

MBS6143653-01mL 0.1(mL
EUR 875

POLR2C (DNA-directed RNA Polymerase II Subunit RPB3, RNA Polymerase II Subunit 3, RNA Polymerase II Subunit B3, DNA-directed RNA Polymerase II 33kD Polypeptide, RPB33, DNA-directed RNA Polymerase II Subunit C, RPB31, A-152E5.7) (Biotin)

MBS6143653-5x01mL 5x0.1mL
EUR 3800

POLR2C (DNA-directed RNA Polymerase II Subunit RPB3, RNA Polymerase II Subunit 3, RNA Polymerase II Subunit B3, DNA-directed RNA Polymerase II 33kD Polypeptide, RPB33, DNA-directed RNA Polymerase II Subunit C, RPB31, A-152E5.7) (FITC)

MBS6148956-01mL 0.1(mL
EUR 875

POLR2C (DNA-directed RNA Polymerase II Subunit RPB3, RNA Polymerase II Subunit 3, RNA Polymerase II Subunit B3, DNA-directed RNA Polymerase II 33kD Polypeptide, RPB33, DNA-directed RNA Polymerase II Subunit C, RPB31, A-152E5.7) (FITC)

MBS6148956-5x01mL 5x0.1mL
EUR 3800

POLR2C (DNA-directed RNA Polymerase II Subunit RPB3, RNA Polymerase II Subunit 3, RNA Polymerase II Subunit B3, DNA-directed RNA Polymerase II 33kD Polypeptide, RPB33, DNA-directed RNA Polymerase II Subunit C, RPB31, A-152E5.7) (HRP)

MBS6154259-01mL 0.1(mL
EUR 875

POLR2C (DNA-directed RNA Polymerase II Subunit RPB3, RNA Polymerase II Subunit 3, RNA Polymerase II Subunit B3, DNA-directed RNA Polymerase II 33kD Polypeptide, RPB33, DNA-directed RNA Polymerase II Subunit C, RPB31, A-152E5.7) (HRP)

MBS6154259-5x01mL 5x0.1mL
EUR 3800

POLR2I (DNA-directed RNA Polymerase II Subunit RPB9, DNA-directed RNA Polymerase II Subunit I, RNA Polymerase II 14.5kD Subunit) (AP)

MBS6133050-01mL 0.1(mL
EUR 875

POLR2I (DNA-directed RNA Polymerase II Subunit RPB9, DNA-directed RNA Polymerase II Subunit I, RNA Polymerase II 14.5kD Subunit) (AP)

MBS6133050-5x01mL 5x0.1mL
EUR 3800

POLR2I (DNA-directed RNA Polymerase II Subunit RPB9, DNA-directed RNA Polymerase II Subunit I, RNA Polymerase II 14.5kD Subunit) (PE)

MBS6159565-01mL 0.1(mL
EUR 875

POLR2I (DNA-directed RNA Polymerase II Subunit RPB9, DNA-directed RNA Polymerase II Subunit I, RNA Polymerase II 14.5kD Subunit) (PE)

MBS6159565-5x01mL 5x0.1mL
EUR 3800

POLR2D (DNA-directed RNA Polymerase II Subunit RPB4, DNA-directed RNA Polymerase II Subunit D, RNA Polymerase II 16kD Subunit) APC

MBS6138351-01mL 0.1(mL
EUR 875

POLR2D (DNA-directed RNA Polymerase II Subunit RPB4, DNA-directed RNA Polymerase II Subunit D, RNA Polymerase II 16kD Subunit) APC

MBS6138351-5x01mL 5x0.1mL
EUR 3800

POLR2I (DNA-directed RNA Polymerase II Subunit RPB9, DNA-directed RNA Polymerase II Subunit I, RNA Polymerase II 14.5kD Subunit) APC

MBS6138353-01mL 0.1(mL
EUR 875

POLR2I (DNA-directed RNA Polymerase II Subunit RPB9, DNA-directed RNA Polymerase II Subunit I, RNA Polymerase II 14.5kD Subunit) APC

MBS6138353-5x01mL 5x0.1mL
EUR 3800

POLR2I (DNA-directed RNA Polymerase II Subunit RPB9, DNA-directed RNA Polymerase II Subunit I, RNA Polymerase II 14.5kD Subunit) (Biotin)

MBS6143656-01mL 0.1(mL
EUR 875

POLR2I (DNA-directed RNA Polymerase II Subunit RPB9, DNA-directed RNA Polymerase II Subunit I, RNA Polymerase II 14.5kD Subunit) (Biotin)

MBS6143656-5x01mL 5x0.1mL
EUR 3800

POLR2D (DNA-directed RNA Polymerase II Subunit RPB4, DNA-directed RNA Polymerase II Subunit D, RNA Polymerase II 16kD Subunit) (AP)

MBS6133048-01mL 0.1(mL
EUR 875

POLR2D (DNA-directed RNA Polymerase II Subunit RPB4, DNA-directed RNA Polymerase II Subunit D, RNA Polymerase II 16kD Subunit) (AP)

MBS6133048-5x01mL 5x0.1mL
EUR 3800

POLR2D (DNA-directed RNA Polymerase II Subunit RPB4, DNA-directed RNA Polymerase II Subunit D, RNA Polymerase II 16kD Subunit) (FITC)

MBS6148957-01mL 0.1(mL
EUR 875

POLR2D (DNA-directed RNA Polymerase II Subunit RPB4, DNA-directed RNA Polymerase II Subunit D, RNA Polymerase II 16kD Subunit) (FITC)

MBS6148957-5x01mL 5x0.1mL
EUR 3800

POLR2I (DNA-directed RNA Polymerase II Subunit RPB9, DNA-directed RNA Polymerase II Subunit I, RNA Polymerase II 14.5kD Subunit) (FITC)

MBS6148959-01mL 0.1(mL
EUR 875

POLR2I (DNA-directed RNA Polymerase II Subunit RPB9, DNA-directed RNA Polymerase II Subunit I, RNA Polymerase II 14.5kD Subunit) (FITC)

MBS6148959-5x01mL 5x0.1mL
EUR 3800

POLR2D (DNA-directed RNA Polymerase II Subunit RPB4, DNA-directed RNA Polymerase II Subunit D, RNA Polymerase II 16kD Subunit) (HRP)

MBS6154260-01mL 0.1(mL
EUR 875

POLR2D (DNA-directed RNA Polymerase II Subunit RPB4, DNA-directed RNA Polymerase II Subunit D, RNA Polymerase II 16kD Subunit) (HRP)

MBS6154260-5x01mL 5x0.1mL
EUR 3800

POLR2I (DNA-directed RNA Polymerase II Subunit RPB9, DNA-directed RNA Polymerase II Subunit I, RNA Polymerase II 14.5kD Subunit) (HRP)

MBS6154262-01mL 0.1(mL
EUR 875

POLR2I (DNA-directed RNA Polymerase II Subunit RPB9, DNA-directed RNA Polymerase II Subunit I, RNA Polymerase II 14.5kD Subunit) (HRP)

MBS6154262-5x01mL 5x0.1mL
EUR 3800

POLR2D (DNA-directed RNA Polymerase II Subunit RPB4, DNA-directed RNA Polymerase II Subunit D, RNA Polymerase II 16kD Subunit) (PE)

MBS6159563-01mL 0.1(mL
EUR 875

POLR2D (DNA-directed RNA Polymerase II Subunit RPB4, DNA-directed RNA Polymerase II Subunit D, RNA Polymerase II 16kD Subunit) (PE)

MBS6159563-5x01mL 5x0.1mL
EUR 3800

POLR2C (DNA-directed RNA Polymerase II Subunit RPB3, RNA Polymerase II Subunit 3, RNA Polymerase II Subunit B3, DNA-directed RNA Polymerase II 33kD Polypeptide, RPB33, DNA-directed RNA Polymerase II Subunit C, RPB31, A-152E5.7) (MaxLight 490)

MBS6202586-01mL 0.1(mL
EUR 875

POLR2C (DNA-directed RNA Polymerase II Subunit RPB3, RNA Polymerase II Subunit 3, RNA Polymerase II Subunit B3, DNA-directed RNA Polymerase II 33kD Polypeptide, RPB33, DNA-directed RNA Polymerase II Subunit C, RPB31, A-152E5.7) (MaxLight 490)

MBS6202586-5x01mL 5x0.1mL
EUR 3800

POLR2C (DNA-directed RNA Polymerase II Subunit RPB3, RNA Polymerase II Subunit 3, RNA Polymerase II Subunit B3, DNA-directed RNA Polymerase II 33kD Polypeptide, RPB33, DNA-directed RNA Polymerase II Subunit C, RPB31, A-152E5.7) (MaxLight 550)

MBS6213261-01mL 0.1(mL
EUR 875

POLR2C (DNA-directed RNA Polymerase II Subunit RPB3, RNA Polymerase II Subunit 3, RNA Polymerase II Subunit B3, DNA-directed RNA Polymerase II 33kD Polypeptide, RPB33, DNA-directed RNA Polymerase II Subunit C, RPB31, A-152E5.7) (MaxLight 550)

MBS6213261-5x01mL 5x0.1mL
EUR 3800

POLR2C (DNA-directed RNA Polymerase II Subunit RPB3, RNA Polymerase II Subunit 3, RNA Polymerase II Subunit B3, DNA-directed RNA Polymerase II 33kD Polypeptide, RPB33, DNA-directed RNA Polymerase II Subunit C, RPB31, A-152E5.7) (MaxLight 405)

MBS6191911-01mL 0.1(mL
EUR 875

POLR2C (DNA-directed RNA Polymerase II Subunit RPB3, RNA Polymerase II Subunit 3, RNA Polymerase II Subunit B3, DNA-directed RNA Polymerase II 33kD Polypeptide, RPB33, DNA-directed RNA Polymerase II Subunit C, RPB31, A-152E5.7) (MaxLight 405)

MBS6191911-5x01mL 5x0.1mL
EUR 3800

POLR2C (DNA-directed RNA Polymerase II Subunit RPB3, RNA Polymerase II Subunit 3, RNA Polymerase II Subunit B3, DNA-directed RNA Polymerase II 33kD Polypeptide, RPB33, DNA-directed RNA Polymerase II Subunit C, RPB31, A-152E5.7) (MaxLight 650)

MBS6223936-01mL 0.1(mL
EUR 875

POLR2C (DNA-directed RNA Polymerase II Subunit RPB3, RNA Polymerase II Subunit 3, RNA Polymerase II Subunit B3, DNA-directed RNA Polymerase II 33kD Polypeptide, RPB33, DNA-directed RNA Polymerase II Subunit C, RPB31, A-152E5.7) (MaxLight 650)

MBS6223936-5x01mL 5x0.1mL
EUR 3800

POLR2C (DNA-directed RNA Polymerase II Subunit RPB3, RNA Polymerase II Subunit 3, RNA Polymerase II Subunit B3, DNA-directed RNA Polymerase II 33kD Polypeptide, RPB33, DNA-directed RNA Polymerase II Subunit C, RPB31, A-152E5.7) (MaxLight 750)

MBS6234611-01mL 0.1(mL
EUR 875

POLR2C (DNA-directed RNA Polymerase II Subunit RPB3, RNA Polymerase II Subunit 3, RNA Polymerase II Subunit B3, DNA-directed RNA Polymerase II 33kD Polypeptide, RPB33, DNA-directed RNA Polymerase II Subunit C, RPB31, A-152E5.7) (MaxLight 750)

MBS6234611-5x01mL 5x0.1mL
EUR 3800

POLR2A (DNA-directed RNA Polymerase II Subunit RPB1, RNA Polymerase II Subunit B1, DNA-directed RNA Polymerase II Subunit A, DNA-directed RNA Polymerase III Largest Subunit, RNA-directed RNA Polymerase II Subunit RPB1, POLR2, MGC75453) APC

MBS6138349-01mL 0.1(mL
EUR 875

POLR2A (DNA-directed RNA Polymerase II Subunit RPB1, RNA Polymerase II Subunit B1, DNA-directed RNA Polymerase II Subunit A, DNA-directed RNA Polymerase III Largest Subunit, RNA-directed RNA Polymerase II Subunit RPB1, POLR2, MGC75453) APC

MBS6138349-5x01mL 5x0.1mL
EUR 3800

POLR2A (DNA-directed RNA Polymerase II Subunit RPB1, RNA Polymerase II Subunit B1, DNA-directed RNA Polymerase II Subunit A, DNA-directed RNA Polymerase III Largest Subunit, RNA-directed RNA Polymerase II Subunit RPB1, POLR2, MGC75453) (Biotin)

MBS6143652-01mL 0.1(mL
EUR 875

POLR2A (DNA-directed RNA Polymerase II Subunit RPB1, RNA Polymerase II Subunit B1, DNA-directed RNA Polymerase II Subunit A, DNA-directed RNA Polymerase III Largest Subunit, RNA-directed RNA Polymerase II Subunit RPB1, POLR2, MGC75453) (Biotin)

MBS6143652-5x01mL 5x0.1mL
EUR 3800

POLR2A (DNA-directed RNA Polymerase II Subunit RPB1, RNA Polymerase II Subunit B1, DNA-directed RNA Polymerase II Subunit A, DNA-directed RNA Polymerase III Largest Subunit, RNA-directed RNA Polymerase II Subunit RPB1, POLR2, MGC75453) (AP)

MBS6133046-01mL 0.1(mL
EUR 875

POLR2A (DNA-directed RNA Polymerase II Subunit RPB1, RNA Polymerase II Subunit B1, DNA-directed RNA Polymerase II Subunit A, DNA-directed RNA Polymerase III Largest Subunit, RNA-directed RNA Polymerase II Subunit RPB1, POLR2, MGC75453) (AP)

MBS6133046-5x01mL 5x0.1mL
EUR 3800

POLR2A (DNA-directed RNA Polymerase II Subunit RPB1, RNA Polymerase II Subunit B1, DNA-directed RNA Polymerase II Subunit A, DNA-directed RNA Polymerase III Largest Subunit, RNA-directed RNA Polymerase II Subunit RPB1, POLR2, MGC75453) (FITC)

MBS6148955-01mL 0.1(mL
EUR 875

POLR2A (DNA-directed RNA Polymerase II Subunit RPB1, RNA Polymerase II Subunit B1, DNA-directed RNA Polymerase II Subunit A, DNA-directed RNA Polymerase III Largest Subunit, RNA-directed RNA Polymerase II Subunit RPB1, POLR2, MGC75453) (FITC)

MBS6148955-5x01mL 5x0.1mL
EUR 3800

POLR2A (DNA-directed RNA Polymerase II Subunit RPB1, RNA Polymerase II Subunit B1, DNA-directed RNA Polymerase II Subunit A, DNA-directed RNA Polymerase III Largest Subunit, RNA-directed RNA Polymerase II Subunit RPB1, POLR2, MGC75453) (HRP)

MBS6154258-01mL 0.1(mL
EUR 875

POLR2A (DNA-directed RNA Polymerase II Subunit RPB1, RNA Polymerase II Subunit B1, DNA-directed RNA Polymerase II Subunit A, DNA-directed RNA Polymerase III Largest Subunit, RNA-directed RNA Polymerase II Subunit RPB1, POLR2, MGC75453) (HRP)

MBS6154258-5x01mL 5x0.1mL
EUR 3800

POLR2A (DNA-directed RNA Polymerase II Subunit RPB1, RNA Polymerase II Subunit B1, DNA-directed RNA Polymerase II Subunit A, DNA-directed RNA Polymerase III Largest Subunit, RNA-directed RNA Polymerase II Subunit RPB1, POLR2, MGC75453) (PE)

MBS6159561-01mL 0.1(mL
EUR 875

POLR2A (DNA-directed RNA Polymerase II Subunit RPB1, RNA Polymerase II Subunit B1, DNA-directed RNA Polymerase II Subunit A, DNA-directed RNA Polymerase III Largest Subunit, RNA-directed RNA Polymerase II Subunit RPB1, POLR2, MGC75453) (PE)

MBS6159561-5x01mL 5x0.1mL
EUR 3800

POLR2D (DNA-directed RNA Polymerase II Subunit RPB4, DNA-directed RNA Polymerase II Subunit D, RNA Polymerase II 16kD Subunit) (Biotin)

MBS6143654-01mL 0.1(mL
EUR 875

POLR2D (DNA-directed RNA Polymerase II Subunit RPB4, DNA-directed RNA Polymerase II Subunit D, RNA Polymerase II 16kD Subunit) (Biotin)

MBS6143654-5x01mL 5x0.1mL
EUR 3800

POLR2A (DNA-directed RNA Polymerase II Subunit RPB1, RNA Polymerase II Subunit B1, DNA-directed RNA Polymerase II Subunit A, DNA-directed RNA Polymerase III Largest Subunit, RNA-directed RNA Polymerase II Subunit RPB1, POLR2, MGC75453) (MaxLight 490)

MBS6202585-01mL 0.1(mL
EUR 875

POLR2A (DNA-directed RNA Polymerase II Subunit RPB1, RNA Polymerase II Subunit B1, DNA-directed RNA Polymerase II Subunit A, DNA-directed RNA Polymerase III Largest Subunit, RNA-directed RNA Polymerase II Subunit RPB1, POLR2, MGC75453) (MaxLight 490)

MBS6202585-5x01mL 5x0.1mL
EUR 3800

POLR2A (DNA-directed RNA Polymerase II Subunit RPB1, RNA Polymerase II Subunit B1, DNA-directed RNA Polymerase II Subunit A, DNA-directed RNA Polymerase III Largest Subunit, RNA-directed RNA Polymerase II Subunit RPB1, POLR2, MGC75453) (MaxLight 550)

MBS6213260-01mL 0.1(mL
EUR 875

POLR2A (DNA-directed RNA Polymerase II Subunit RPB1, RNA Polymerase II Subunit B1, DNA-directed RNA Polymerase II Subunit A, DNA-directed RNA Polymerase III Largest Subunit, RNA-directed RNA Polymerase II Subunit RPB1, POLR2, MGC75453) (MaxLight 550)

MBS6213260-5x01mL 5x0.1mL
EUR 3800

POLR2A (DNA-directed RNA Polymerase II Subunit RPB1, RNA Polymerase II Subunit B1, DNA-directed RNA Polymerase II Subunit A, DNA-directed RNA Polymerase III Largest Subunit, RNA-directed RNA Polymerase II Subunit RPB1, POLR2, MGC75453) (MaxLight 405)

MBS6191910-01mL 0.1(mL
EUR 875

POLR2A (DNA-directed RNA Polymerase II Subunit RPB1, RNA Polymerase II Subunit B1, DNA-directed RNA Polymerase II Subunit A, DNA-directed RNA Polymerase III Largest Subunit, RNA-directed RNA Polymerase II Subunit RPB1, POLR2, MGC75453) (MaxLight 405)

MBS6191910-5x01mL 5x0.1mL
EUR 3800

POLR2A (DNA-directed RNA Polymerase II Subunit RPB1, RNA Polymerase II Subunit B1, DNA-directed RNA Polymerase II Subunit A, DNA-directed RNA Polymerase III Largest Subunit, RNA-directed RNA Polymerase II Subunit RPB1, POLR2, MGC75453) (MaxLight 650)

MBS6223935-01mL 0.1(mL
EUR 875

POLR2A (DNA-directed RNA Polymerase II Subunit RPB1, RNA Polymerase II Subunit B1, DNA-directed RNA Polymerase II Subunit A, DNA-directed RNA Polymerase III Largest Subunit, RNA-directed RNA Polymerase II Subunit RPB1, POLR2, MGC75453) (MaxLight 650)

MBS6223935-5x01mL 5x0.1mL
EUR 3800

POLR2A (DNA-directed RNA Polymerase II Subunit RPB1, RNA Polymerase II Subunit B1, DNA-directed RNA Polymerase II Subunit A, DNA-directed RNA Polymerase III Largest Subunit, RNA-directed RNA Polymerase II Subunit RPB1, POLR2, MGC75453) (MaxLight 750)

MBS6234610-01mL 0.1(mL
EUR 875

POLR2A (DNA-directed RNA Polymerase II Subunit RPB1, RNA Polymerase II Subunit B1, DNA-directed RNA Polymerase II Subunit A, DNA-directed RNA Polymerase III Largest Subunit, RNA-directed RNA Polymerase II Subunit RPB1, POLR2, MGC75453) (MaxLight 750)

MBS6234610-5x01mL 5x0.1mL
EUR 3800

POLR2D, ID (POLR2D, DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerase II subunit D, RNA polymerase II 16kD subunit)

MBS6002083-02mL 0.2(mL
EUR 695

POLR2D, ID (POLR2D, DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerase II subunit D, RNA polymerase II 16kD subunit)

MBS6002083-5x02mL 5x0.2mL
EUR 2975

POLR2D (DNA-directed RNA Polymerase II Subunit RPB4, DNA-directed RNA Polymerase II Subunit D, RNA Polymerase II 16kD Subunit) (MaxLight 490)

MBS6202587-01mL 0.1(mL
EUR 875

POLR2D (DNA-directed RNA Polymerase II Subunit RPB4, DNA-directed RNA Polymerase II Subunit D, RNA Polymerase II 16kD Subunit) (MaxLight 490)

MBS6202587-5x01mL 5x0.1mL
EUR 3800

POLR2I (DNA-directed RNA Polymerase II Subunit RPB9, DNA-directed RNA Polymerase II Subunit I, RNA Polymerase II 14.5kD Subunit) (MaxLight 490)

MBS6202589-01mL 0.1(mL
EUR 875

POLR2I (DNA-directed RNA Polymerase II Subunit RPB9, DNA-directed RNA Polymerase II Subunit I, RNA Polymerase II 14.5kD Subunit) (MaxLight 490)

MBS6202589-5x01mL 5x0.1mL
EUR 3800

POLR2D (DNA-directed RNA Polymerase II Subunit RPB4, DNA-directed RNA Polymerase II Subunit D, RNA Polymerase II 16kD Subunit) (MaxLight 550)

MBS6213262-01mL 0.1(mL
EUR 875

POLR2D (DNA-directed RNA Polymerase II Subunit RPB4, DNA-directed RNA Polymerase II Subunit D, RNA Polymerase II 16kD Subunit) (MaxLight 550)

MBS6213262-5x01mL 5x0.1mL
EUR 3800

POLR2I (DNA-directed RNA Polymerase II Subunit RPB9, DNA-directed RNA Polymerase II Subunit I, RNA Polymerase II 14.5kD Subunit) (MaxLight 550)

MBS6213264-01mL 0.1(mL
EUR 875

POLR2I (DNA-directed RNA Polymerase II Subunit RPB9, DNA-directed RNA Polymerase II Subunit I, RNA Polymerase II 14.5kD Subunit) (MaxLight 550)

MBS6213264-5x01mL 5x0.1mL
EUR 3800

POLR2D (DNA-directed RNA Polymerase II Subunit RPB4, DNA-directed RNA Polymerase II Subunit D, RNA Polymerase II 16kD Subunit) (MaxLight 405)

MBS6191912-01mL 0.1(mL
EUR 875

POLR2D (DNA-directed RNA Polymerase II Subunit RPB4, DNA-directed RNA Polymerase II Subunit D, RNA Polymerase II 16kD Subunit) (MaxLight 405)

MBS6191912-5x01mL 5x0.1mL
EUR 3800

POLR2I (DNA-directed RNA Polymerase II Subunit RPB9, DNA-directed RNA Polymerase II Subunit I, RNA Polymerase II 14.5kD Subunit) (MaxLight 405)

MBS6191914-01mL 0.1(mL
EUR 875

POLR2I (DNA-directed RNA Polymerase II Subunit RPB9, DNA-directed RNA Polymerase II Subunit I, RNA Polymerase II 14.5kD Subunit) (MaxLight 405)

MBS6191914-5x01mL 5x0.1mL
EUR 3800

POLR2D (DNA-directed RNA Polymerase II Subunit RPB4, DNA-directed RNA Polymerase II Subunit D, RNA Polymerase II 16kD Subunit) (MaxLight 650)

MBS6223937-01mL 0.1(mL
EUR 875

POLR2D (DNA-directed RNA Polymerase II Subunit RPB4, DNA-directed RNA Polymerase II Subunit D, RNA Polymerase II 16kD Subunit) (MaxLight 650)

MBS6223937-5x01mL 5x0.1mL
EUR 3800

POLR2I (DNA-directed RNA Polymerase II Subunit RPB9, DNA-directed RNA Polymerase II Subunit I, RNA Polymerase II 14.5kD Subunit) (MaxLight 650)

MBS6223939-01mL 0.1(mL
EUR 875

POLR2I (DNA-directed RNA Polymerase II Subunit RPB9, DNA-directed RNA Polymerase II Subunit I, RNA Polymerase II 14.5kD Subunit) (MaxLight 650)

MBS6223939-5x01mL 5x0.1mL
EUR 3800

POLR2D (DNA-directed RNA Polymerase II Subunit RPB4, DNA-directed RNA Polymerase II Subunit D, RNA Polymerase II 16kD Subunit) (MaxLight 750)

MBS6234612-01mL 0.1(mL
EUR 875

POLR2D (DNA-directed RNA Polymerase II Subunit RPB4, DNA-directed RNA Polymerase II Subunit D, RNA Polymerase II 16kD Subunit) (MaxLight 750)

MBS6234612-5x01mL 5x0.1mL
EUR 3800

POLR2I (DNA-directed RNA Polymerase II Subunit RPB9, DNA-directed RNA Polymerase II Subunit I, RNA Polymerase II 14.5kD Subunit) (MaxLight 750)

MBS6234614-01mL 0.1(mL
EUR 875

POLR2I (DNA-directed RNA Polymerase II Subunit RPB9, DNA-directed RNA Polymerase II Subunit I, RNA Polymerase II 14.5kD Subunit) (MaxLight 750)

MBS6234614-5x01mL 5x0.1mL
EUR 3800

RNA polymerase II-IN-1

HY-147916 Get quote Ask for price
Description: RNA polymerase II-IN-1 (compound 19iv) is a amatoxin, inhibiting RNA polymerase II (Pol II) with an IC50 value of 36.66 nM. RNA polymerase II-IN-1 has higher cytotoxicity against cancer cells and less toxic in normal cells than α-Amanitin[1].

RNA polymerase II-IN-2

HY-147917 Get quote Ask for price
Description: RNA polymerase II-IN-2 (compound 20iii) is a potent RNA polymerase II (Pol II) inhibitor with Ki value of 9.5 nM. RNA polymerase II-IN-2 has cytotoxicity against cancer cells, and exhibits 2 and 5 fold toxicity than α-amanitin against CHO and HEK293[1].

POLR2G, CT (POLR2G, RPB7, DNA-directed RNA polymerase II subunit RPB7, DNA-directed RNA polymerase II subunit G, RNA polymerase II 19kD subunit)

MBS6003712-02mL 0.2(mL
EUR 695

POLR2G, CT (POLR2G, RPB7, DNA-directed RNA polymerase II subunit RPB7, DNA-directed RNA polymerase II subunit G, RNA polymerase II 19kD subunit)

MBS6003712-5x02mL 5x0.2mL
EUR 2975

POLR2G, CT (POLR2G, RPB7, DNA-directed RNA polymerase II subunit RPB7, DNA-directed RNA polymerase II subunit G, RNA polymerase II 19kD subunit)

MBS6005568-02mL 0.2(mL
EUR 695

POLR2G, CT (POLR2G, RPB7, DNA-directed RNA polymerase II subunit RPB7, DNA-directed RNA polymerase II subunit G, RNA polymerase II 19kD subunit)

MBS6005568-5x02mL 5x0.2mL
EUR 2975

POLR2D, ID (POLR2D, DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerase II subunit D, RNA polymerase II 16kD subunit) (AP)

MBS6335697-02mL 0.2mL
EUR 980

POLR2D, ID (POLR2D, DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerase II subunit D, RNA polymerase II 16kD subunit) (AP)

MBS6335697-5x02mL 5x0.2mL
EUR 4250

POLR2D, ID (POLR2D, DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerase II subunit D, RNA polymerase II 16kD subunit) (APC)

MBS6335698-02mL 0.2mL
EUR 980

POLR2D, ID (POLR2D, DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerase II subunit D, RNA polymerase II 16kD subunit) (APC)

MBS6335698-5x02mL 5x0.2mL
EUR 4250

POLR2D, ID (POLR2D, DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerase II subunit D, RNA polymerase II 16kD subunit) (FITC)

MBS6335700-02mL 0.2mL
EUR 980

POLR2D, ID (POLR2D, DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerase II subunit D, RNA polymerase II 16kD subunit) (FITC)

MBS6335700-5x02mL 5x0.2mL
EUR 4250

POLR2D, ID (POLR2D, DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerase II subunit D, RNA polymerase II 16kD subunit) (PE)

MBS6335707-02mL 0.2mL
EUR 980

POLR2D, ID (POLR2D, DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerase II subunit D, RNA polymerase II 16kD subunit) (PE)

MBS6335707-5x02mL 5x0.2mL
EUR 4250

RNA polymerase II CTD Antibody

GWB-225CEF 0.1 mg Ask for price

POLR2D, ID (POLR2D, DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerase II subunit D, RNA polymerase II 16kD subunit) (Biotin)

MBS6335699-02mL 0.2mL
EUR 980

POLR2D, ID (POLR2D, DNA-directed RNA polymerase II subunit RPB4, DNA-directed RNA polymerase II subunit D, RNA polymerase II 16kD subunit) (Biotin)

MBS6335699-5x02mL 5x0.2mL
EUR 4250

RNA polymerase II RBP8 Antibody

GWB-80D2DE 0.05 ml Ask for price

RNA polymerase II RPB11 Antibody

GWB-81535B 0.05 ml Ask for price

POLR2G, CT (POLR2G, RPB7, DNA-directed RNA polymerase II subunit RPB7, DNA-directed RNA polymerase II subunit G, RNA polymerase II 19kD subunit) (AP)

MBS6335719-02mL 0.2mL
EUR 980

POLR2G, CT (POLR2G, RPB7, DNA-directed RNA polymerase II subunit RPB7, DNA-directed RNA polymerase II subunit G, RNA polymerase II 19kD subunit) (AP)

MBS6335719-5x02mL 5x0.2mL
EUR 4250

POLR2G, CT (POLR2G, RPB7, DNA-directed RNA polymerase II subunit RPB7, DNA-directed RNA polymerase II subunit G, RNA polymerase II 19kD subunit) (APC)

MBS6335720-02mL 0.2mL
EUR 980

Conclusions
We have shown the importance of the immunosuppression and the delayed graft function as factors that modify the overall expression of the PBMC ARNA-TLR for a period of time after the KT. Patients with a DGF story chronically reduce the expression of the TLR2, TLR3, TLR4 and TLR9 mRNA. This fact is associated with a worst transplant function. Measuring the expression of the TLR in the upper range of therapeutic doses of Calcineurin and MMF inhibitors offers the possibility of assessing the strength, efficiency and toxicity of immunosuppression.

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