List Of Ligand Binding Assay

Cereblon Binding Assay Kit
79899 96 rxns.
EUR 600
Description: The Cereblon Binding Assay Kit (FP) is designed for testing and profiling of Cereblon (CRBN) inhibitors using Fluorescence Polarization. The assay is a competitive binding assay, based on the binding of fluorescently-labeled Thalidomide, a CRBN binder, to purified recombinant CRBN._x000D_ CRBN is the substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. CRBN is a direct protein target for the immunomodulatory and antiproliferative activities of thalidomide analogues such as lenalidomide and pomalidomide._x000D_ The Cereblon Binding Assay Kit (FP) comes in a convenient 96-well format, with enough purified CRBN, Cy5-labeled Thalidomide, and assay buffer for 100 enzyme reactions. In addition, the kit includes the CRBN inhibitor Pomalidomide for use as an inhibitor control._x000D_
The key to the CRBN Assay Kit is the fluorescently-labeled Thalidomide. Using this kit, only one simple step on a microtiter plate is required for CRBN reactions. The Cy5-labeled Thalidomide is incubated with a sample containing CRBN to produce a change in fluorescent polarization that can be measured using a fluorescence reader.

Binding Assay Laboratories manufactures the list of ligand binding assay reagents distributed by Genprice. The List Of Ligand Binding Assay reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact binding assay. Other List products are available in stock. Specificity: List Category: Of Group: Ligand Binding

HDL and LDL/VLDL Assay Kit
100 assays
EUR 898

PCSK9[Biotinylated]-LDLR Binding Assay Kit
96 rxns.
EUR 805
Description: The PCSK9[Biotinylated]-LDLR Binding Assay Kit is designed for screening and profiling purposes. The key to this kit is the high sensitivity of detection of biotin-labeled PCSK9 by streptavidin-HRP. Only a few simple steps on a microtiter plate are required for the assay. First, LDLR ectodomain is coated on a 96-well plate. Next, PCSK9 is incubated with LDLR on the plate. Finally, the plate is treated with streptavidin-HRP followed by addition of an HRP substrate to produce chemiluminescence, which can then be measured using a chemiluminescence reader.

Mouse Chemokine Ligand 2 (CCL2) Detecton Assay Kit
1 kit
EUR 580.26
Description: Mouse Chemokine Ligand 2 (CCL2) Detecton Assay Kit

Mouse Chemokine Ligand 5 (CCL5) Detection Assay Kit
1 kit
EUR 580.26
Description: Mouse Chemokine Ligand 5 (CCL5) Detection Assay Kit

Mouse Chemokine Ligand 25 (CCL25) Detection Assay Kit
1 kit
EUR 580.26
Description: Mouse Chemokine Ligand 25 (CCL25) Detection Assay Kit

Total Iron-Binding Capacity (TIBC) and Serum Iron Assay Kit (Colorimetric)
each
EUR 698.4

XTT CELL VIABILITY ASSAY KIT (1000 ASSAY)
1KIT
EUR 283.2
Description: Minimum order quantity: 1 unit of 1KIT

Ligand Binding information

Amplite® Human Serum Albumin (HSA) Site II Binding Assay Kit
25402 200 Tests
EUR 318

Amplite® Human Serum Albumin (HSA) Site I Binding Assay Kit
25400-200Tests 200 Tests
EUR 318
Description: Human serum albumin (HSA) is one of the most important carriers for acidic drugs in human plasma and has been shown to bind a large number of different compounds in a reversible manner.

Amplite® Human Serum Albumin (HSA) Site II Binding Assay Kit
25402-200Tests 200 Tests
EUR 318
Description: Human serum albumin (HSA) is one of the most important carriers for acidic drugs in human plasma and has been shown to bind a large number of different compounds in a reversible manner.

Beta Amyloid 1- 42 (A?42) Ligand Screening Assay Kit (Fluorometric)
K570-100 each
EUR 679.2

Cell Meterâ„¢ Live Cell Caspase 8 Binding Assay Kit *Red Fluorescence*
20116-25Tests 25 Tests
EUR 372
Description: Our Cell Meterâ„¢ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

EpiQuik BRD2 Binding Activity/Inhibition Assay Kit (Colorimetric)
P-4058 96 Assays
EUR 1032.66

Cell Meterâ„¢ Live Cell Caspase 1 Binding Assay Kit *Green Fluorescence*
20108-25Tests 25 Tests
EUR 334
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meterâ„¢ Live Cell Caspase 2 Binding Assay Kit *Green Fluorescence*
20111-25Tests 25 Tests
EUR 334
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meterâ„¢ Live Cell Caspase 6 Binding Assay Kit *Green Fluorescence*
20113-25Tests 25 Tests
EUR 334
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meterâ„¢ Live Cell Caspase 8 Binding Assay Kit *Green Fluorescence*
20115-25Tests 25 Tests
EUR 334
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meterâ„¢ Live Cell Caspase 9 Binding Assay Kit *Green Fluorescence*
20117-25Tests 25 Tests
EUR 334
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meterâ„¢ Live Cell Caspase 10 Binding Assay Kit *Green Fluorescence*
20119-25Tests 25 Tests
EUR 334
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meterâ„¢ Live Cell Caspase 13 Binding Assay Kit *Green Fluorescence*
20125-25Tests 25 Tests
EUR 334
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meter™ Live Cell Caspase 8 Binding Assay Kit *Red Fluorescence*
20116 25 Tests
EUR 372

Cell Meterâ„¢ Live Cell Caspase 3/7 Binding Assay Kit *Red Fluorescence*
20101-25Tests 25 Tests
EUR 334
Description: Our Cell Meter™ live cell caspases activity assay kits are based on fluorescent FMK inhibitors of caspases.

Cell Meter™ Live Cell Caspase 1 Binding Assay Kit *Green Fluorescence*
20108 25 Tests
EUR 334

Cell Meter™ Live Cell Caspase 2 Binding Assay Kit *Green Fluorescence*
20111 25 Tests
EUR 334