M30 Apoptosense Ligand Binding Assay

Cereblon Binding Assay Kit
79899 96 rxns.
EUR 600
Description: The Cereblon Binding Assay Kit (FP) is designed for testing and profiling of Cereblon (CRBN) inhibitors using Fluorescence Polarization. The assay is a competitive binding assay, based on the binding of fluorescently-labeled Thalidomide, a CRBN binder, to purified recombinant CRBN._x000D_ CRBN is the substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. CRBN is a direct protein target for the immunomodulatory and antiproliferative activities of thalidomide analogues such as lenalidomide and pomalidomide._x000D_ The Cereblon Binding Assay Kit (FP) comes in a convenient 96-well format, with enough purified CRBN, Cy5-labeled Thalidomide, and assay buffer for 100 enzyme reactions. In addition, the kit includes the CRBN inhibitor Pomalidomide for use as an inhibitor control._x000D_
The key to the CRBN Assay Kit is the fluorescently-labeled Thalidomide. Using this kit, only one simple step on a microtiter plate is required for CRBN reactions. The Cy5-labeled Thalidomide is incubated with a sample containing CRBN to produce a change in fluorescent polarization that can be measured using a fluorescence reader.

Binding Assay Laboratories manufactures the m30 apoptosense ligand binding assay reagents distributed by Genprice. The M30 Apoptosense Ligand Binding Assay reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact binding assay. Other M30 products are available in stock. Specificity: M30 Category: Apoptosense Group: Ligand Binding

Retinol binding protein Assay Kit
R1：45ml×1R2：15ml×1
EUR 1000

UGT Activity Assay / Ligand Screening Kit (Fluorometric)
each
EUR 588

PPAR? Ligand Screening/Characterization Assay Kit (Fluorometric)
each
EUR 1161.6

Creatinine Assay Kit (urine normalizing assay)
1Kit
EUR 220

Creatinine Assay Kit (urine normalizing assay)
5x1Kit
EUR 960

Antibiotic Assay Medium No.3 (Assay
1 unit
EUR 14.77
Description: Antibiotic Assay Medium No.3 (Assay

Antibiotic Assay Medium No.3 (Assay
1 unit
EUR 41.3
Description: Antibiotic Assay Medium No.3 (Assay

Ligand Binding information

LXRB-LBD. Purified GST-tagged human Liver X receptor beta ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.
N1H2 50 ug
EUR 498
Description: Drug discovery, Nuclear receptors, purified recombinant protein

LXRA-LBD. Purified GST-tagged human Liver X receptor alpha ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.
N1H3 50 ug
EUR 360
Description: Drug discovery, Nuclear receptors, purified recombinant protein

RXRA-LBD. Purified GST-tagged human Retinoid X receptor alpha ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.
N2B1 50 ug
EUR 360
Description: Drug discovery, Nuclear receptors, purified recombinant protein

RXRB-LBD. Purified GST-tagged human Retinoid X receptor beta ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.
N2B2 50 ug
EUR 360
Description: Drug discovery, Nuclear receptors, purified recombinant protein

RXRG-LBD. Purified GST-tagged human Retinoid X receptor gamma ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.
N2B3 50 ug
EUR 360
Description: Drug discovery, Nuclear receptors, purified recombinant protein

ESRRA-LBD. Purified GST-tagged human Estrogen-related receptor alpha ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.
N3B1 50 ug
EUR 980
Description: Drug discovery, Nuclear receptors, purified recombinant protein

ESRRB-LBD. Purified GST-tagged human Estrogen-related receptor beta ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.
N3B2 50 ug
EUR 498
Description: Drug discovery, Nuclear receptors, purified recombinant protein

ESRRG-LBD. Purified GST-tagged human Estrogen-related receptor gamma ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.
N3B3 50 ug
EUR 360
Description: Drug discovery, Nuclear receptors, purified recombinant protein

THRB-LBD. Purified GST-tagged human Thyroid hormone receptor beta ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.
N1A2 50 ug
EUR 660
Description: Drug discovery, Nuclear receptors, purified recombinant protein

RARA-LBD. Purified GST-tagged human Retinoic acid receptor alpha ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.
N1B1 50 ug
EUR 498
Description: Drug discovery, Nuclear receptors, purified recombinant protein

RARG-LBD. Purified GST-tagged human Retinoic acid receptor gamma ligand binding domain. Applications: Ligand-binding and coregulator displacement assays.
N1B3 50 ug
EUR 498
Description: Drug discovery, Nuclear receptors, purified recombinant protein

TRAIL (TNF-Related Apoptosis Inducing Ligand, Apo2 Ligand) (AP)
MBS6121835-01mL 0.1(mL
EUR 750

TRAIL (TNF-Related Apoptosis Inducing Ligand, Apo2 Ligand) (AP)
MBS6121835-5x01mL 5x0.1mL
EUR 3235

TRAIL (TNF-Related Apoptosis Inducing Ligand, Apo2 Ligand) (PE)
MBS6122075-01mL 0.1(mL
EUR 750

TRAIL (TNF-Related Apoptosis Inducing Ligand, Apo2 Ligand) (PE)
MBS6122075-5x01mL 5x0.1mL
EUR 3235

TRAIL (TNF-Related Apoptosis Inducing Ligand, Apo2 Ligand) (APC)
MBS6121883-01mL 0.1(mL
EUR 750

TRAIL (TNF-Related Apoptosis Inducing Ligand, Apo2 Ligand) (APC)
MBS6121883-5x01mL 5x0.1mL
EUR 3235