Human Flt-3 LigandFlt3L Antibody

Anti-Human Flt-3 Ligand Antibody

102-P14 100 µg
EUR 245.7
Description: Flt-3 Ligand, also known as FL, is an α-helical cytokine that promotes the differentiation of multiple hematopoietic cell lineages. Mature human Flt-3 Ligand consists of a 158 amino acid (aa) extracellular domain (ECD) with a cytokine-like domain and a juxtamembrane region, a 21 aa transmembrane segment, and a 30 aa cytoplasmic tail. Within the ECD, human Flt-3 Ligand shares 71% and 65% aa sequence identity with mouse and rat Flt-3 Ligand, respectively. Human and mouse Flt-3 Ligand show cross-species activity. Flt-3 Ligand is expressed as a non-covalently linked dimer by T cells and bone marrow and thymic fibroblasts. Each 36 kDa chain carries approximately 12 kDa of N- and O-linked carbohydrates. Alternate splicing and proteolytic cleavage of the transmembrane form can generate a soluble 30 kDa fragment that includes the cytokine domain. Alternate splicing of human Flt -3 Ligand also generates membraneassociated isoforms that contain either a truncated cytoplasmic tail or an 85 aa substitution following the cytokine domain. Both transmembrane and soluble Flt-3 Ligand signal through the tyrosine kinase receptor Flt3/ FlK-1. Flt-3 Ligand induces the expansion of monocytes and immature dendritic cells as well as early B cell lineage differentiation.

Human Antibody Laboratories manufactures the human flt-3 ligand/flt3l antibody reagents distributed by Genprice. The Human Flt-3 Ligand/Flt3L Antibody reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact human Antibody. Other Human products are available in stock. Specificity: Human Category: Flt-3 Group: Ligand/Flt3L Antibody

FMS Like Tyrosine Kinase 3 Ligand (Flt3L) Antibody

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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

FMS Like Tyrosine Kinase 3 Ligand (Flt3L) Antibody

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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

FMS Like Tyrosine Kinase 3 Ligand (Flt3L) Antibody

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  • 1 mg
  • 200 ug

Flt-3 Ligand Recombinant Protein

0.1 mg
EUR 714.3
Description: FMS-like tyrosine kinase 3 ligand (Flt-3 Ligand) is also known as FL, Flt3L and FLT3LG, is an α-helical cytokine that promotes the differentiation of multiple hematopoietic cell lineages. FLT3LG is expressed as a noncovalentlylinked dimer by T cells and bone marrow and thymic fibroblasts. Each 36 kDa chain carries approximately 12 kDa of N- and O- linked carbohydrates. FLT3LG is structurally homologous to stem cell factor (SCF) and colony stimulating facor 1 (CSF-1). FLT3LG acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. It also induces the mobilization of the hematopoietic progenitors and stem cells in vivo which may help the system to kill cancer cells. FLT3LG induces the expansion of monocytes and immature dendritic cells as well as early B cell lineage differentiation. FLT3LG cooperates with IL2, IL6, IL7, and IL15 to induce NK cell development and with IL3, IL7 and IL11 to induce terminal B cell maturation. Animal studies also show FLT3LG to reduce the severity of experimentally induced allergic inflammation. FLT3LG is crucial for steady-state pDC and cDC development. A lack of FLT3L results in low levels of DCs.

Flt-3 Ligand Recombinant Protein

0.1 mg
EUR 714.3
Description: FMS-like tyrosine kinase 3 ligand (Flt-3 Ligand) is also known as FL, Flt3L and FLT3LG, is an α-helical cytokine that promotes the differentiation of multiple hematopoietic cell lineages. FLT3LG is expressed as a noncovalentlylinked dimer by T cells and bone marrow and thymic fibroblasts. Each 36 kDa chain carries approximately 12 kDa of N- and O- linked carbohydrates. FLT3LG is structurally homologous to stem cell factor (SCF) and colony stimulating facor 1 (CSF-1). FLT3LG acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. It also induces the mobilization of the hematopoietic progenitors and stem cells in vivo which may help the system to kill cancer cells. FLT3LG induces the expansion of monocytes and immature dendritic cells as well as early B cell lineage differentiation. FLT3LG cooperates with IL2, IL6, IL7, and IL15 to induce NK cell development and with IL3, IL7 and IL11 to induce terminal B cell maturation. Animal studies also show FLT3LG to reduce the severity of experimentally induced allergic inflammation. FLT3LG is crucial for steady-state pDC and cDC development. A lack of FLT3L results in low levels of DCs.

flt-3-Ligand, murine recombinant

each
EUR 294

flt-3-Ligand, murine recombinant

each
EUR 4953.6

Ligand/Flt3L Antibody information

FMS Like Tyrosine Kinase 3 Ligand (Flt3L) Monoclonal Antibody

CAU30575-200ul 200ul
EUR 252

Active Recombinant Human Flt3 ligand/Flt3L Protein

RP00175 5 μg
EUR 65

Monoclonal Antibody to FMS Like Tyrosine Kinase 3 Ligand (Flt3L)

MAA038Hu21 100ul
EUR 210

Monoclonal Antibody to FMS Like Tyrosine Kinase 3 Ligand (Flt3L)

MAA038Hu22 100ul
EUR 203

Polyclonal Antibody to FMS Like Tyrosine Kinase 3 Ligand (Flt3L)

PAA038Mu01 100ul
EUR 160

Polyclonal Antibody to FMS Like Tyrosine Kinase 3 Ligand (Flt3L)

PAA038Mu02 100ul
EUR 227

FMS Like Tyrosine Kinase 3 Ligand (Flt3L) Polyclonal Antibody (Mouse)

4-PAA038Mu01
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse FMS Like Tyrosine Kinase 3 Ligand (Flt3L)

FMS Like Tyrosine Kinase 3 Ligand (Flt3L) Polyclonal Antibody (Mouse)

4-PAA038Mu02
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse FMS Like Tyrosine Kinase 3 Ligand (Flt3L)

Recombinant Human FLT3L/Flt3 ligand/FLT3LG Protein, His Tag

E40KMP1183 20ug
EUR 495

Flt3l (untagged) - Mouse FMS-like tyrosine kinase 3 ligand (Flt3l), (10ug)

MC208499 10 µg Ask for price

Human FMS Like Tyrosine Kinase 3 Ligand (Flt3L) Protein

20-abx652063
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

FMS Like Tyrosine Kinase 3 Ligand (Flt3L) Polyclonal Antibody (Mouse), PE

4-PAA038Mu01-PE
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse FMS Like Tyrosine Kinase 3 Ligand (Flt3L). This antibody is labeled with PE.

FMS Like Tyrosine Kinase 3 Ligand (Flt3L) Polyclonal Antibody (Mouse), PE

4-PAA038Mu02-PE
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse FMS Like Tyrosine Kinase 3 Ligand (Flt3L). This antibody is labeled with PE.

FMS Like Tyrosine Kinase 3 Ligand (Flt3L) Polyclonal Antibody (Mouse), APC

4-PAA038Mu01-APC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse FMS Like Tyrosine Kinase 3 Ligand (Flt3L). This antibody is labeled with APC.

FMS Like Tyrosine Kinase 3 Ligand (Flt3L) Polyclonal Antibody (Mouse), Cy3

4-PAA038Mu01-Cy3
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse FMS Like Tyrosine Kinase 3 Ligand (Flt3L). This antibody is labeled with Cy3.

FMS Like Tyrosine Kinase 3 Ligand (Flt3L) Polyclonal Antibody (Mouse), HRP

4-PAA038Mu01-HRP
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse FMS Like Tyrosine Kinase 3 Ligand (Flt3L). This antibody is labeled with HRP.

FMS Like Tyrosine Kinase 3 Ligand (Flt3L) Polyclonal Antibody (Mouse), APC

4-PAA038Mu02-APC
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse FMS Like Tyrosine Kinase 3 Ligand (Flt3L). This antibody is labeled with APC.